Determination of the serum level of aluminum & zinc in hemodialysis patients in Kerman,Iran

Abstract

Dialysis is one of the effective methods which has been used since 1955 for the treatment of patients suffering from renal failure( more often of its chronic type). The dialysis results in the elimination of waste materials like urea and creatinine from the body, on the other hand, it can affect the serum contamination of the dialysis fluid. Aluminium is one of trace elements which its serum level increases in patient undergoing hemodialysis. This increase of serum concentration of aluminium, effects the metabolism of iron. In this study, the serum level of aluminium and zinc in patients subjected to hemodialysis were evaluated. The subjects were 56 hemodialysis patient and the control were 36 healthy appearing people. Aluminium and zinc serum concentration determined using flameless atomic absorption spectroscopy. The results indicated that: 1) the mean serum concentration of aluminium( 0.272+_0.128 ppm) shows a significant increase in the patient group, compared with the control group (0.016+_0.005 ppm) ( p<0.05). 2) the mean serum concentration of zinc (0.806+_0.177 ppm) in these patients shows no significant increase compared with control group (0.767+_0.159 ppm).