A Japanese case of amoebic meningoencephalitis initially diagnosed by cerebrospinal fluid cytology

Abstract

Abstract Microscopy can detect the presence of amoebic trophozoites in cerebrospinal fluid and tissue. The infection was confirmed in the present case by polymerase chain reaction and immunohistochemistry, but we were unable to achieve a cure. Our case rapidly progressed without any skin lesions.

Keywords

• Balamuthia mandrillaris amoebic meningoencephalitis
• cerebrospinal fluid
• cytology
• Free‐living amoebae
• immunohistochemistry
• PCR