Effects of Ibuprofen Use on Lymphocyte Count and Oxidative Stress in Elite Paralympic Powerlifting
Felipe J. Aidar,
Guacira S. Fraga,
Márcio Getirana-Mota,
Anderson Carlos Marçal,
Jymmys L. Santos,
Raphael Fabricio de Souza,
Alexandre Reis Pires Ferreira,
Eduardo Borba Neves,
Aristela de Freitas Zanona,
Alexandre Bulhões-Correia,
Paulo Francisco de Almeida-Neto,
Tulio Luiz Banja Fernandes,
Nuno Domingos Garrido,
Maria do Socorro Cirilo-Sousa,
María Merino-Fernández,
Alfonso López Díaz-de-Durana,
Eugenia Murawska-Ciałowicz,
Breno Guilherme de Araújo Tinoco Cabral,
Filipe Manuel Clemente
Affiliations
Felipe J. Aidar
Graduate Program of Physical Education, Federal University of Sergipe (UFS), São Cristovão 49100-000, Brazil
Guacira S. Fraga
Graduate Program of Physical Education, Federal University of Sergipe (UFS), São Cristovão 49100-000, Brazil
Márcio Getirana-Mota
Graduate Program of Physical Education, Federal University of Sergipe (UFS), São Cristovão 49100-000, Brazil
Anderson Carlos Marçal
Graduate Program of Physical Education, Federal University of Sergipe (UFS), São Cristovão 49100-000, Brazil
Jymmys L. Santos
Graduate Program of Physical Education, Federal University of Sergipe (UFS), São Cristovão 49100-000, Brazil
Raphael Fabricio de Souza
Graduate Program of Physical Education, Federal University of Sergipe (UFS), São Cristovão 49100-000, Brazil
Alexandre Reis Pires Ferreira
College of Physical Education and Exercise Science, University of Brasília (UnB), Brasília 70910-900, Brazil
Eduardo Borba Neves
Graduate Program in Biomedical Engineering, Federal Technological University of Paraná (UTFPR), Curitiba 80230-901, Brazil
Aristela de Freitas Zanona
Department of Occupational Therapy, Federal University of Sergipe (UFS), Lagarto 49400-000, Brazil
Alexandre Bulhões-Correia
Department of Physical Education, Federal University of Rio Grande do Norte, Natal 59064-741, Brazil
Paulo Francisco de Almeida-Neto
Department of Physical Education, Federal University of Rio Grande do Norte, Natal 59064-741, Brazil
Tulio Luiz Banja Fernandes
Institute of Physical Education and Sport, Federal University of Ceará (UFC), Fortaleza 60020-181, Brazil
Nuno Domingos Garrido
Research Center in Sports Sciences, Health Sciences and Human Development (CIDESD), University of Trás-os-Montes e Alto Douro, 5001-801 Vila Real, Portugal
Maria do Socorro Cirilo-Sousa
Graduate Program Association of Physical Education, Federal University of Paraíba (UFPB), João Pessoa 58051-900, Brazil
María Merino-Fernández
Faculty of Health Sciences, Universidad Francisco de Vitoria (UFV), 28223 Madrid, Spain
Alfonso López Díaz-de-Durana
Sports Department, Physical Activity and Sports Faculty-INEF, Universidad Politécnica de Madrid, 28040 Madrid, Spain
Eugenia Murawska-Ciałowicz
Physiology and Biochemistry Department, University School of Physical Education, 51-612 Wroclaw, Poland
Breno Guilherme de Araújo Tinoco Cabral
Department of Physical Education, Federal University of Rio Grande do Norte, Natal 59064-741, Brazil
Filipe Manuel Clemente
Escola Superior Desporto e Lazer, Instituto Politécnico de Viana do Castelo, Rua Escola Industrial e Comercial de Nun’Álvares, 4900-347 Viana do Castelo, Portugal
Background: Paralympic Powerlifting (PP) training tends to promote fatigue and oxidative stress. Objective: To analyze the effects of ibuprofen use on performance and oxidative stress in post-training PP athletes. Methodology: Ten national level PP athletes (age: 27.13 ± 5.57) were analyzed for oxidative stress in post-training. The study was carried out in three weeks, (1) familiarization and (2 and 3) evaluated the recovery with the use of a placebo (PLA) and ibuprofen (IBU), 800 mg. The Peak Torque (PT), Torque Development Rate (TDR), Fatigue Index (FI), reactive substances to thiobarbituric acid (TBARS) and sulfhydryl groups (SH) were evaluated. The training consisted of five sets of five repetitions (80–90%) 1-Repetition Maximum (1-RM) in the bench press. Results: The IBU showed a higher PT (24 and 48 h, p = 0.04, ɳ2 p = 0.39), a lower FI (24 h, p = 0.01, ɳ2p = 0.74) and an increased lymphocyte count (p 2p = 4.36). There was no change in oxidative stress. Conclusions: The use of IBU provided improvements in strength and did not protect against oxidative stress.
