Frontiers in Neurology (Aug 2022)

EEG background frequency is associated with discharge outcomes in non-ICU hospitalized patients with COVID-19

  • Kaitlin M. Seibert,
  • Wonhee Lee,
  • Alexandra Eid,
  • Amy E. Espinal,
  • Sara A. Klein,
  • Sumayyah K. Abumurad,
  • James X. Tao,
  • Naoum P. Issa

DOI
https://doi.org/10.3389/fneur.2022.941903
Journal volume & issue
Vol. 13

Abstract

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ObjectiveTo assess risk factors for encephalopathy in non-ICU hospitalized patients with COVID-19 and the effect of encephalopathy on short-term outcomes.MethodsWe collected clinical and electrophysiological characteristics of fifty patients with COVID-19 infection admitted to a ward service and who had an electroencephalogram (EEG) performed. Associations with short-term outcomes including hospital length of stay and discharge disposition were determined from univariate and multivariate statistical analysis.ResultsClinical delirium was associated with encephalopathy on EEG, cefepime use was associated with increased length of stay, and of all factors analyzed, background frequency on EEG alone was correlated with discharge disposition.ConclusionEncephalopathy is one of the major determinants of short-term outcomes in hospitalized non-ICU patients with COVID-19.

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