An Association of Galanin with some biochemical parameters in Iraqi Type II Diabetic Patients

Abstract

Body's ability to produce insulin is affected by a group of chronic metabolic diseases known as diabetes. present study tried to explore whether there was any association of galanin with urea, uric acid, creatinine, albumin, globulin, total protein, albumin-to-globulin ratio, fasting glucose in patients with type 2 diabetes.This study included 43 patients, 43 healthy controls (HCs). ELISA was used to determine level of galanin. Study found that level of serum galanin in patients with T2DM was higher compared to healthy subjects (P 6.14 ng/mL), FSG (> 116.5 mg/dL), Urea (> 30.5 mg/dL), Uric acid ( 0.835 mg/dL), T. Protein ( 2.75 g/dL) and ALB/GLB (< 1.545). Conclusion: Serum galanin may be used as a biomarker in detection of T2DM and may be an effective biomarker in the diagnostic test for T2DM.

Keywords

• type 2 diabetes,,
• ,،galanin,,,
• ,،insulin,,,
• ,،total protein