Journal of Investigative Medicine High Impact Case Reports (Jun 2021)

Atraumatic Splenic Rupture in a Patient on Apixaban and Dual Antiplatelet Therapy

  • Piruthiviraj Natarajan MD,
  • Sudhagar Thangarasu MD, FACP,
  • Lela Ruck MD,
  • Paul Estrada MD,
  • Mahesh Gajendran MD, MPH,
  • Gowri Renganathan MD,
  • Bharat Ved Prakash MD,
  • Olufemi Aduroja MD, MPH

DOI
https://doi.org/10.1177/23247096211026492
Journal volume & issue
Vol. 9

Abstract

Read online

Splenic rupture due to any cause is a life-threatening complication and commonly attributed to trauma. Atraumatic splenic rupture is very rarely reported, and the incidence is currently unknown. Anticoagulants and dual anti-platelet medication can increase the chances of a splenic rupture. Surgical removal of the spleen may be warranted to prevent a life-threatening bleeding. Early identification and intervention are required for most patients as only a few qualify for medical management.