پزشکی بالینی ابن سینا (Dec 2002)
A Comparison of Anesthetic Effects between Intrathecal Meperidine and Lidocaine 5% for TURP Operation
Abstract
The aim of this study was a comparison between intrathecal meperidine and lidocaine 5% for onset of sensory blockade, level of sensory block, degree of motor blockade , duration of postoperative analgesia, hemodynamic changes, degree of nausea and Vomiting, pruritus and shivering for T.U.R Operation. 60 patients with ASA I-III were divided randomly into intrathecal meperidine goup (n=30) and 5% lidocaine group (n=30). The first group received 1 mg/kg (2ml) meperidine and the second group received 100 mg of 5% lidocaine (2ml). Thirty minutes before subarachnoid puncture all of the patients received 500ml ringer solution. Subarachnoid puncture was performed with the patient in the sitting position using a 23 gauge spinal needle at the lumbar level of L3-L4 and the patient immediately in the supine position. The onset time for sensory blockade was 3.99 minutes in the lidocaine group and 5 minutes in the meperidine group. The segmental level of analgesia was present in 28 patients in the lidicaine group .Duration of post operative analgesia was 354 minutes in the lidicanie group and 662 minute in the meperidine group. Systolic arterial blood pressure and heart rate did not change significantly , and there was no difference between meperidine and lidocaine groups. Complication such as nausea and vomiting were similar in the two groups, but pruritus was seen only in patients receiving meperidine , and intraoperative sedation occurred in patients receiving meperidine more than the other group. No patients who received meperidine had postoperative shivering. So according to this study, Intrathecal meperidine used alone has advantages over lidocaine 5% for T.U.R. operation.
