Recommendations for addressing the translational gap between experimental and clinical research on amyloid diseases

Abstract

Abstract This paper is a report of recommendations for addressing translational challenges in amyloid disease research. They were developed during and following an international online workshop organized by the LINXS Institute of Advanced Neutron and X-Ray Science in March 2021. Key suggestions include improving cross-cultural communication between basic science and clinical research, increasing the influence of scientific societies and journals (vis-à-vis funding agencies and pharmaceutical companies), improving the dissemination of negative results, and strengthening the ethos of science.

Keywords

• Amyloid diseases
• Translational medicine
• Alzheimer’s disease
• Negative results
• Complexity
• Heterogeneity