Quantitative evaluation of the clinical severity of hemoglobin H disease in a cohort of 591 patients using a scoring system based on regression analysis

• Yumeng Liu,
• Yuan Zhuang,
• Jianhong Chen,
• Zeyan Zhong,
• Jianpei Fang,
• Xinyu Li,
• Bin Xiao,
• Pingping Li,
• Bin Lin,
• Zhenzhong Tao,
• Yidan Liang,
• Peng Lin,
• Xingmin Wang,
• Mengyang Song,
• Hualei Luo,
• Lang Qin,
• Li Huang,
• Jufang Tan,
• Hailiang Li,
• Tianyu Zhong,
• Lian Yu,
• Zhixiang Liu,
• Deguo Tang,
• Yongzhong Zhao,
• Xinhua Zhang,
• Yuhua Ye,
• Xiangmin Xu

Affiliations

Yumeng Liu

Innovation Center for Diagnostics and Treatment of Thalassemia, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong, China; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, Guangdong

Yuan Zhuang

Innovation Center for Diagnostics and Treatment of Thalassemia, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong, China; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, Guangdong

Jianhong Chen

Department of Medical Genetics and Prenatal Diagnosis, Huizhou First Maternal and Child Health Care Hospital, Huizhou, Guangdong, 516001

Zeyan Zhong

Department of Medical Genetics and Prenatal Diagnosis, Huizhou First Maternal and Child Health Care Hospital, Huizhou, Guangdong, 516001

Jianpei Fang

Department of Pediatric Hematology/Oncology, Children’s Medical Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120

Xinyu Li

Department of Pediatric Hematology/Oncology, Children’s Medical Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120

Bin Xiao

Department of Hematology, 923(rd) Hospital of the People's Liberation Army, Nanning, Guangxi 530021

Pingping Li

Department of Hematology, 923(rd) Hospital of the People's Liberation Army, Nanning, Guangxi 530021

Bin Lin

Guangzhou Huayin Healthcare Group Co., Ltd., Guangzhou 510663, Guangdong, China; Guangzhou Jiexu Gene Technology Co., Ltd., Guangzhou 510530, Guangdong

Zhenzhong Tao

Guangzhou Huayin Healthcare Group Co., Ltd., Guangzhou 510663, Guangdong, China; Guangzhou Jiexu Gene Technology Co., Ltd., Guangzhou 510530, Guangdong

Yidan Liang

Innovation Center for Diagnostics and Treatment of Thalassemia, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong, China; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, Guangdong

Peng Lin

Innovation Center for Diagnostics and Treatment of Thalassemia, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong, China; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, Guangdong

Xingmin Wang

Innovation Center for Diagnostics and Treatment of Thalassemia, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong, China; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, Guangdong

Mengyang Song

Innovation Center for Diagnostics and Treatment of Thalassemia, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong, China; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, Guangdong

Hualei Luo

Innovation Center for Diagnostics and Treatment of Thalassemia, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong, China; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, Guangdong

Lang Qin

Innovation Center for Diagnostics and Treatment of Thalassemia, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong, China; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, Guangdong

Li Huang

Innovation Center for Diagnostics and Treatment of Thalassemia, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong, China; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, Guangdong

Jufang Tan

Prenatal Diagnosis Center, Chenzhou First People's Hospital Chenzhou 423000, Hunan

Hailiang Li

Department of Laboratory Hematology, The First Affiliated Hospital of Gannan Medical University, Ganzhou 341000, Jiangxi

Tianyu Zhong

Department of Laboratory Medicine, The First Affiliated Hospital of Gannan Medical University, Ganzhou 341000, Jiangxi

Lian Yu

Department of Hematology and Rheumatology, Longyan First Hospital, Affiliated to Fujian Medical University, Longyan 364000

Zhixiang Liu

Department of Medical Dispute, Maternal and Child Health Hospital, Heyuan517000

Deguo Tang

Maternal and Child Health Hospital of Yongzhou City, Yongzhou, Hunan 425000

Yongzhong Zhao

Biologics,Gene and Cell Therapy, Frontage Laboratories, 760 Pennsylvania Dr, Exton, PA, 19341

Xinhua Zhang

Department of Hematology, 923(rd) Hospital of the People's Liberation Army, Nanning, Guangxi 530021

Yuhua Ye

Innovation Center for Diagnostics and Treatment of Thalassemia, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong, China; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, Guangdong

Xiangmin Xu

Innovation Center for Diagnostics and Treatment of Thalassemia, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong, China; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, Guangdong