Journal of Immunology Research (Jan 2016)

The Memories of NK Cells: Innate-Adaptive Immune Intrinsic Crosstalk

  • Sara Gabrielli,
  • Claudio Ortolani,
  • Genny del Zotto,
  • Francesca Luchetti,
  • Barbara Canonico,
  • Flavia Buccella,
  • Marco Artico,
  • Stefano Papa,
  • Loris Zamai

DOI
https://doi.org/10.1155/2016/1376595
Journal volume & issue
Vol. 2016

Abstract

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Although NK cells are considered part of the innate immune system, a series of evidences has demonstrated that they possess characteristics typical of the adaptive immune system. These NK adaptive features, in particular their memory-like functions, are discussed from an ontogenetic and evolutionary point of view.