Palladium-Catalysed Coupling and Acid-Mediated Cyclisation: Synthesis of Fluorenones and Fluorenes

Abstract

Abstract Palladium-catalysed sequential one-pot synthesis of fluorenones is described. The reaction comprises intermolecular Suzuki coupling and intramolecular acid-mediated cyclisation in a one-pot procedure. The protocol is also applied to the synthesis of fluorenes using a single column purification.

Keywords

• friedel–crafts
• cyclocarbonylation
• fluorenone
• fluorine