Nature Communications (Jul 2019)

Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism

  • Julien Robert-Paganin,
  • James P. Robblee,
  • Daniel Auguin,
  • Thomas C. A. Blake,
  • Carol S. Bookwalter,
  • Elena B. Krementsova,
  • Dihia Moussaoui,
  • Michael J. Previs,
  • Guillaume Jousset,
  • Jake Baum,
  • Kathleen M. Trybus,
  • Anne Houdusse

DOI
https://doi.org/10.1038/s41467-019-11120-0
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 12

Abstract

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Here, Robert-Paganin et al. show that myosin A from Plasmodium falciparum is critical for red blood cell invasion and that non-canonical interactions and regulated phosphorylation are important for force generation during parasite invasion.