Frontiers in Pediatrics (Feb 2022)

Case Report: Persistency Pneumococcal Polysaccharide in Cerebrospinal Fluid During a Post Pneumococcal Chronic Aseptic Meningitis: Coincidental or (Auto-)Inflammatory Embers

  • Manon Ladeveze,
  • Yann Dumont,
  • G. Boursier,
  • Frederic Batteux,
  • Perrine Mahe,
  • Aurelie Bensimon Borrull,
  • Guillaume Sarrabay,
  • Karine Bollore,
  • Karine Bollore,
  • Edouard Tuaillon,
  • Edouard Tuaillon,
  • Edouard Tuaillon,
  • Sylvain Godreuil,
  • Sylvain Godreuil,
  • Eric Jeziorski,
  • Eric Jeziorski

DOI
https://doi.org/10.3389/fped.2022.762457
Journal volume & issue
Vol. 10

Abstract

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We report the case of a 9-months-old boy that has presented a steroid-dependent post-pneumococcal chronic aseptic meningitis was associated with persistence of pneumococcal cell wall components in cerebrospinal fluid during more than 20 months. Suggesting that this antigenic persistence could be involved in post-infectious manifestations through innate immunity response.

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