A retrospective chart review assessing antibiotic treatment of hospitalized patients with discordant Clostridioides difficile assays in an urban hospitalized setting

Clare Stoddart; Irene Kuo; Matthew A. Spence; Tara N. Palmore

doi:10.1017/ash.2024.60

Antimicrobial Stewardship & Healthcare Epidemiology (Jan 2024)

A retrospective chart review assessing antibiotic treatment of hospitalized patients with discordant Clostridioides difficile assays in an urban hospitalized setting

Clare Stoddart,
Irene Kuo,
Matthew A. Spence,
Tara N. Palmore

Affiliations

Clare Stoddart: ORCiD; The George Washington University Milken Institute School of Public Health, Washington, DC, USA
Irene Kuo: ORCiD; Department of Epidemiology, The George Washington University Milken Institute School of Public Health, Washington, DC, USA
Matthew A. Spence: The George Washington University Hospital, Washington, DC, USA
Tara N. Palmore: The George Washington University School of Medicine & Health Sciences, Washington, DC, USA

DOI: https://doi.org/10.1017/ash.2024.60
Journal volume & issue: Vol. 4

Abstract

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Clostridioides difficile infection (CDI) threatens vulnerable populations in health care. Two-step testing improves specificity, avoiding over-treatment. This study analyzed inpatient records to estimate diagnostic outcomes and identify characteristics associated with treatment after discordant testing. Among discordant patients, those aged 65+ years were significantly more likely to be prescribed antibiotics (67% vs 39%).

Published in Antimicrobial Stewardship & Healthcare Epidemiology

ISSN: 2732-494X (Online)
Publisher: Cambridge University Press
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases; Medicine: Public aspects of medicine
Website: https://www.cambridge.org/core/journals/antimicrobial-stewardship-and-healthcare-epidemiology

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