The role of the dystrophin glycoprotein complex in muscle cell mechanotransduction

Darren Graham Samuel Wilson; Andrew Tinker; Thomas Iskratsch

doi:10.1038/s42003-022-03980-y

Communications Biology (Sep 2022)

The role of the dystrophin glycoprotein complex in muscle cell mechanotransduction

Darren Graham Samuel Wilson,
Andrew Tinker,
Thomas Iskratsch

Affiliations

Darren Graham Samuel Wilson: School of Engineering and Materials Science, Queen Mary University of London
Andrew Tinker: William Harvey Research Institute, Queen Mary University of London
Thomas Iskratsch: School of Engineering and Materials Science, Queen Mary University of London

DOI: https://doi.org/10.1038/s42003-022-03980-y
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 18

Abstract

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A review of the function of the Dystrophic Glycoprotein Complex (DGC) in mechanosignaling provides an overview of the various components of DGC and potential mechanopathogenic mechanisms, particularly as they relate to muscular dystrophy.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal