JACS Au (Jun 2024)
Application of Directed Evolution and Machine Learning to Enhance the Diastereoselectivity of Ketoreductase for Dihydrotetrabenazine Synthesis
- Chenming Huang,
- Li Zhang,
- Tong Tang,
- Haijiao Wang,
- Yingqian Jiang,
- Hanwen Ren,
- Yitian Zhang,
- Jiali Fang,
- Wenhe Zhang,
- Xian Jia,
- Song You,
- Bin Qin
Affiliations
- Chenming Huang
- Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China
- Li Zhang
- Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China
- Tong Tang
- Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China
- Haijiao Wang
- Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China
- Yingqian Jiang
- Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China
- Hanwen Ren
- Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China
- Yitian Zhang
- Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China
- Jiali Fang
- Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China
- Wenhe Zhang
- School of Life Sciences and Biopharmaceutical Sciences, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China
- Xian Jia
- School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China
- Song You
- School of Life Sciences and Biopharmaceutical Sciences, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China
- Bin Qin
- Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China
- DOI
- https://doi.org/10.1021/jacsau.4c00284
- Journal volume & issue
-
Vol. 4,
no. 7
pp. 2547 – 2556
Abstract
No abstracts available.
