One-pot H/D exchange and low-coordinated iron electrocatalyzed deuteration of nitriles in D2O to α,β-deuterio aryl ethylamines

Abstract

One-pot efficient synthesis of α,β-deuterio aryl ethylamines with high deuterium ratios using an easy-to-handle deuterated source under ambient conditions is desirable. Here the author report the electrosynthesis of α,β-deuterio aryl ethylamines from aryl acetonitriles using D2O.