Clinicopathologic characteristics and survival outcomes of primary mucosal melanomas: A 10-year retrospective analysis from a single tertiary medical center in Thailand

Abstract

Primary mucosal melanoma is a rare, aggressive neoplasm and there is limited data in Asian. We aim is to describe the clinicopathologic features and to evaluate overall survival rate (OS). We reviewed 17 cases over a 10-year period. The mean age was 60.9 ± 14.8 with 94.1% being female. The female genital tract was the principal location (52.9%). The most presenting symptoms were masses (88.2%), with 44.1% being amelanotic melanoma. The majority of patients (41.2%) had TNM stage IV. The median OS was 19.5 months, whilst the 1- and 3-year OS were; 70.6% (95% CI, 51.9–95.9%) and 9.8% (95% CI, 1.6–59.5%), respectively. Keywords: Anorectal, Female genital tract, Head and neck, Primary mucosal melanoma, Survival outcome