Communications Biology (Jun 2022)
Genetic, parental and lifestyle factors influence telomere length
- Sergio Andreu-Sánchez,
- Geraldine Aubert,
- Aida Ripoll-Cladellas,
- Sandra Henkelman,
- Daria V. Zhernakova,
- Trishla Sinha,
- Alexander Kurilshikov,
- Maria Carmen Cenit,
- Marc Jan Bonder,
- Lude Franke,
- Cisca Wijmenga,
- Jingyuan Fu,
- Monique G. P. van der Wijst,
- Marta Melé,
- Peter Lansdorp,
- Alexandra Zhernakova
Affiliations
- Sergio Andreu-Sánchez
- Department of Genetics, University of Groningen, University Medical Center Groningen
- Geraldine Aubert
- Terry Fox Laboratory, British Columbia Cancer Research Center
- Aida Ripoll-Cladellas
- Life Sciences Department, Barcelona Supercomputing Center
- Sandra Henkelman
- European Research Institute for the Biology of Ageing, University of Groningen
- Daria V. Zhernakova
- Department of Genetics, University of Groningen, University Medical Center Groningen
- Trishla Sinha
- Department of Genetics, University of Groningen, University Medical Center Groningen
- Alexander Kurilshikov
- Department of Genetics, University of Groningen, University Medical Center Groningen
- Maria Carmen Cenit
- Department of Genetics, University of Groningen, University Medical Center Groningen
- Marc Jan Bonder
- Department of Genetics, University of Groningen, University Medical Center Groningen
- Lude Franke
- Department of Genetics, University of Groningen, University Medical Center Groningen
- Cisca Wijmenga
- Department of Genetics, University of Groningen, University Medical Center Groningen
- Jingyuan Fu
- Department of Genetics, University of Groningen, University Medical Center Groningen
- Monique G. P. van der Wijst
- Department of Genetics, University of Groningen, University Medical Center Groningen
- Marta Melé
- Life Sciences Department, Barcelona Supercomputing Center
- Peter Lansdorp
- Terry Fox Laboratory, British Columbia Cancer Research Center
- Alexandra Zhernakova
- Department of Genetics, University of Groningen, University Medical Center Groningen
- DOI
- https://doi.org/10.1038/s42003-022-03521-7
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 14
Abstract
Deep molecular and phenotypic data highlights the links of human telomere lengths from six different blood cells with genetics, parental phenotypes mediated by epigenetic signals and expression changes at the single cell level.