Severe thrombocytopenia in primary EBV- Infection with no signs of infectious mononucleosis. A case report
Maria Pishmisheva-Peleva,
Stanislav Kotsev,
Djahide Emin,
Naum Simonoski,
Martina Shopova,
Radka Argirova
Affiliations
Maria Pishmisheva-Peleva
Department of Infectious Diseases, Pazardzhik Multiprofile Hospital for Active Treatment, Pazardzhik, Bulgaria; Correspondence to: Department of Infectious Diseases, Pazardzhik Multiprofile Hospital for Active Treatment, 15 Bolnichna str, 4400 Pazardzhik, Bulgaria.
Stanislav Kotsev
Department of Infectious Diseases, Pazardzhik Multiprofile Hospital for Active Treatment, Pazardzhik, Bulgaria
Djahide Emin
Second Department of Internal Diseases – Haematology Ward, Pazardzhik Multiprofile Hospital for Active Treatment, Pazardzhik, Bulgaria
Naum Simonoski
National Specialised Hospital for Active Treatment of Haematological Diseases, Sofia, Bulgaria
Martina Shopova
Department of Infectious Diseases, Pazardzhik Multiprofile Hospital for Active Treatment, Pazardzhik, Bulgaria
Radka Argirova
Laboratory of Virology, Acibadem City Clinic, Tokuda Hospital, Sofia, Bulgaria
Epstein-Barr virus is a widely spread Herpesvirus. Primary EBV infection affects children and young people, inducing haematological changes, with lymphocytosis being the most common. Moderate symptomless thrombocytopenia is found in 50% of the patients, however, severe thrombocytopenia is exceptionally rare. We present a case report of a 20-year-old man with an acute EBV infection, severe thrombocytopenia, and no signs of infectious mononucleosis.
