Progress of CD8+CD25+regulatory T cells in diseases

WEN Li-na, CHEN Li, DUAN Rui, LI Fang

doi:10.16352/j.issn.1001-6325.2022.12.1939

Jichu yixue yu linchuang (Dec 2022)

Progress of CD8+CD25+regulatory T cells in diseases

WEN Li-na, CHEN Li, DUAN Rui, LI Fang

Affiliations

WEN Li-na, CHEN Li, DUAN Rui, LI Fang: Department of Rheumatology and Immunology,the Second Hospital of Shanxi Medical University, Taiyuan 030000,China

DOI: https://doi.org/10.16352/j.issn.1001-6325.2022.12.1939
Journal volume & issue: Vol. 42, no. 12
pp. 1939 – 1944

Abstract

Read online

CD8+CD25+Treg can inhibit immune response and induce immune tolerance. This article reviews the changes and underlying mechanisms of CD8+CD25+Treg in pathogenesis of malignant tumors, autoimmune diseases and other common diseases such as asthma, allergic diseases, type 2 diabetes, and pre-eclampsia. The changes of CD8+CD25+Treg in different diseases are inconsistent, cell counting increased in malignant diseases but decreased in autoimmune diseases. Further understanding of CD8+CD25+Treg would supporte a basis for the prevention, treatment and improving prognosis of these diseases.

cd8+cd25+treg|cd8+ treg|regulatory t cells|autoimmune diseases|tumors

Published in Jichu yixue yu linchuang

ISSN: 1001-6325 (Print)
Publisher: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
Country of publisher: China
LCC subjects: Medicine
Website: http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/1001-6325/home.shtml

About the journal

Abstract

Keywords