Indian Journal of Urology (Jan 2009)

Bleomycin induced urethral stricture in Hodgkin′s disease

  • Ritesh Tapkire,
  • N Kathiresan,
  • B Satheesan

DOI
https://doi.org/10.4103/0970-1591.56180
Journal volume & issue
Vol. 25, no. 3
pp. 398 – 400

Abstract

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Bleomycin is a glycoprotein that is extensively used in combination with other anti-cancer agents because of its relative lack of hematological and gastrointestinal toxicity. However, pulmonary toxicity is common with bleomycin and limits its therapeutic utility. Urethral stricture as a result of bleomycin toxicity has not been reported in literature. In this case report, a young male patient who developed urethral stricture after bleomycin-based chemotherapy is described and the possible effects of bleomycin on the urethra are discussed.

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