Mucocutaneous manifestations of Cowden's syndrome

Abstract

Cowden's syndrome is an autosomal dominant genodermatosis with variable orofacial and systemic manifestations. Here we present one such classical case of Cowden's syndrome in a 45-year-old female patient with features such as multiple cutaneous papillomatosis, oral fibromas, and fibromas involving multiple organs such as gastrointestinal tract (multiple polyps), thyroid disorders, and breast cancer.

Keywords

• Cowden's disease
• hamartomas
• oral papillomatosis
• trichilemmomas