Annals of Hepatology (Dec 2022)

Susceptibility to liver damage in women due to risky alcohol consumption

  • E Morales-Mairena,
  • F Higuera-de la Tijera,
  • A Enríquez-Constantino,
  • DA Santana Vargas,
  • JL Pérez-Hernández

Journal volume & issue
Vol. 27
p. 100814

Abstract

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Introduction and Objectives: Liver damage from alcohol consumption is different between genders, and the susceptibility shown by women is greater than that of men; there are several factors for this difference to exist. We evaluated the complications of cirrhosis due to alcohol in a group of women and compared it with a group of men. This study aimed to compare the effect of alcohol consumption and complications between both genders. Materials and methods: An observational, descriptive, and analytical study compares the pattern of alcohol consumption, the number of grams of alcohol between men and women, and its complications. Results: Two hundred and twenty-two patients were included; 122 women (55.0%) with 51.7±11.5 years of age, Child-Pugh A=24 (10.8%), B=69 (30.6%) and C=130 (58.6%). The grammage/day of alcohol was Women 175.6.9±131.4 and Men 301.5±106.7. The type of consumption was regular risk M=6.6%; excessive M=45.9% and H=58.0%; intoxication M=11.5% and H=8.0%; binge M=36.1% and H=34.0%.Next, the comparison of medians with the Mann-Whitney U test for MIH by type of consumption with significant differences is described. Table 1. Conclusions: It was found that women develop more liver damage and more complications with lower consumption of grams of alcohol. Funding: The resources used in this study were from the hospital without any additional financing Declaration of interest: The authors declare no potential conflicts of interest.