Synthesis, characterization and antibacterial activities of Mo(VI) and Cu(II) complexes derived from tridentate ONO Schiff base ligands

Abstract

Dioxomolybdenum(VI) and copper(II) complexes were synthesized using H2L1 and H2L2 tridentate Schiff base ligands. The ligands were derived from the condensation 2-hydroxy-4-methoxysalicylaldehyde or 2-hydroxy-4-methoxyacetophenone with 2-aminopropanol, respectively. Both complexes were characterized by physico-chemical and spectroscopic methods. Dimeric nature of the Mo(VI) complexes was revealed by IR spectroscopy. Furthermore, MoO2L2(VI) nanoparticles were synthesized by Ultrasonic irradiation.. Elemental analysis, scanning electron microscopy, and FT-IR spectroscopy were used to characterize the nanoparticles. The Schiff base ligands and their complexes have been studied for antibacterial activity against Gram positive and Gram negative bacteria. The results indicated that the Mo(VI) and Cu(II) complexes were effective against all of studied bacteria and its effectiveness was higher for, Escherichia coli.

Keywords

• antibacterial activities
• molybdenum schiff base complexes
• nanoparticles
• ultrasonic irradiation