In a rodent model of autism, probiotics decrease gut leakiness in relation to gene expression of GABA receptors: Emphasize how crucial the gut–brain axis

Bin-Khattaf Rawan M.; Al-Dbass Abeer M.; Alonazi Mona; Bhat Ramesa Shafi; Al-Daihan Sooad; El-Ansary Afaf K.

doi:10.1515/tnsci-2022-0354

Translational Neuroscience (Oct 2024)

In a rodent model of autism, probiotics decrease gut leakiness in relation to gene expression of GABA receptors: Emphasize how crucial the gut–brain axis

Bin-Khattaf Rawan M.,
Al-Dbass Abeer M.,
Alonazi Mona,
Bhat Ramesa Shafi,
Al-Daihan Sooad,
El-Ansary Afaf K.

Affiliations

Bin-Khattaf Rawan M.: Biochemistry Department, Science College, King Saud University, P.O. Box 22452, Riyadh, 11495, Saudi Arabia
Al-Dbass Abeer M.: Biochemistry Department, Science College, King Saud University, P.O. Box 22452, Riyadh, 11495, Saudi Arabia
Alonazi Mona: Biochemistry Department, Science College, King Saud University, P.O. Box 22452, Riyadh, 11495, Saudi Arabia
Bhat Ramesa Shafi: Biochemistry Department, Science College, King Saud University, P.O. Box 22452, Riyadh, 11495, Saudi Arabia
Al-Daihan Sooad: Biochemistry Department, Science College, King Saud University, P.O. Box 22452, Riyadh, 11495, Saudi Arabia
El-Ansary Afaf K.: Autism Center, Lotus Holistic Medical Center, Abu Dhabi, 110281, United Arab Emirates

DOI: https://doi.org/10.1515/tnsci-2022-0354
Journal volume & issue: Vol. 15, no. 1
pp. 24 – 36

Abstract

Read online

Rodent models may help investigations on the possible link between autism spectrum disorder and increased permeability of the gastrointestinal (GI) tract since autistic patients frequently manifested GI troubles as comorbidities.

Published in Translational Neuroscience

ISSN: 2081-6936 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
Website: http://www.degruyter.com/view/j/tnsci

About the journal

Abstract

Keywords