Non-Specific Granulomatous Prostatitis: A Diagnosis of Exclusion

Abstract

Granulomatous prostatitis is a rare inflammatory condition of prostate. The diagnosis of this entity continues to remain a clinical surprise for the treating urologist. They represent a clinical diagnostic dilemma as some of the cases mimic malignancy. The radiological findings and serum prostate specific antigen levels are non- specific in their diagnosis. The definitive diagnosis can be established only by histopathological examination. It is essential to typify the granulomatous prostatitis histologically, so as to guide the management. The presence of Langhans type and foreign body type giant cells with the presence of necrosis does not confirm the diagnosis of tubercular prostatitis, confirmation in fact requires Ziehl-Neelsen staining and tubercular polymerase chain reaction. Nonspecific granulomatous prostatitis represents the majority of the cases of granulomatous prostatitis.

Keywords

• granuloma
• tubercular polymerase chain reaction
• ziehl-neelsen staining