Nature Communications (Dec 2022)

Bead-jet printing enabled sparse mesenchymal stem cell patterning augments skeletal muscle and hair follicle regeneration

  • Yuanxiong Cao,
  • Jiayi Tan,
  • Haoran Zhao,
  • Ting Deng,
  • Yunxia Hu,
  • Junhong Zeng,
  • Jiawei Li,
  • Yifan Cheng,
  • Jiyuan Tang,
  • Zhiwei Hu,
  • Keer Hu,
  • Bing Xu,
  • Zitian Wang,
  • Yaojiong Wu,
  • Peter E. Lobie,
  • Shaohua Ma

DOI
https://doi.org/10.1038/s41467-022-35183-8
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 21

Abstract

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Current mesenchymal stem cell (MSC) transplantation practices are limited by the loss or reduced performance of MSCs. Here the authors develop a bead-jet printer for intraoperative formulation and printing of MSCs-laden Matrigel beads to improve skeletal muscle and hair follicle regeneration.