Antibiotics (Oct 2024)

Can a Shorter Dwell Time Reduce Infective Complications Associated with the Use of Umbilical Catheters?

  • Martina Buttera,
  • Lucia Corso,
  • Leonardo Casadei,
  • Cinzia Valenza,
  • Francesca Sforza,
  • Francesco Candia,
  • Francesca Miselli,
  • Cecilia Baraldi,
  • Licia Lugli,
  • Alberto Berardi,
  • Lorenzo Iughetti

DOI
https://doi.org/10.3390/antibiotics13100988
Journal volume & issue
Vol. 13, no. 10
p. 988

Abstract

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Background: Umbilical venous catheters (UVCs) are the standard of care in neonatal intensive care units (NICUs) to administer fluids, parenteral nutrition and medications, although complications may occur, including central line-associated blood stream infections (CLABSIs). However, the dwell time to reduce CLABSI risk remains an open issue. Methods: We performed a single-center retrospective study of newborns hospitalized in the Modena NICU with at least one UVC inserted over a 6-year period (period 1: January 2011–December 2013; period 2: January 2019–December 2021). We selected a non-consecutive 6-year period to emphasize the differences in UVC management practices that have occurred over time in our NICU. The UVC dwell time and catheter-related complications during the first 4 weeks of life were examined. Results: The UVC dwell time was shorter in period 2 (median 4 days vs. 5 days, p p = 0.5425). However, in period 2, there was an increased need for peripherally inserted central catheters (PICCs) after UVC removal, with a rise in PICC infections after UVC removal (p = 0.0239). Conclusions: In our NICU, shortening UVC dwell time from 5 to 4 days did not decrease the UVC-related complications. Instead, the earlier removal of UVCs led to a higher number of PICCs inserted, possibly increasing the overall infectious risk.

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