Italian Journal of Pediatrics (2021-04-01)

Inter-society consensus for the use of inhaled corticosteroids in infants, children and adolescents with airway diseases

  • Marzia Duse,
  • Francesca Santamaria,
  • Maria Carmen Verga,
  • Marcello Bergamini,
  • Giovanni Simeone,
  • Lucia Leonardi,
  • Giovanna Tezza,
  • Annamaria Bianchi,
  • Annalisa Capuano,
  • Fabio Cardinale,
  • Giovanni Cerimoniale,
  • Massimo Landi,
  • Monica Malventano,
  • Mariangela Tosca,
  • Attilio Varricchio,
  • Anna Maria Zicari,
  • Carlo Alfaro,
  • Salvatore Barberi,
  • Paolo Becherucci,
  • Roberto Bernardini,
  • Paolo Biasci,
  • Carlo Caffarelli,
  • Valeria Caldarelli,
  • Carlo Capristo,
  • Serenella Castronuovo,
  • Elena Chiappini,
  • Renato Cutrera,
  • Giovanna De Castro,
  • Luca De Franciscis,
  • Fabio Decimo,
  • Iride Dello Iacono,
  • Lucia Diaferio,
  • Maria Elisa Di Cicco,
  • Caterina Di Mauro,
  • Cristina Di Mauro,
  • Dora Di Mauro,
  • Francesco Di Mauro,
  • Gabriella Di Mauro,
  • Mattia Doria,
  • Raffaele Falsaperla,
  • Valentina Ferraro,
  • Vassilios Fanos,
  • Elena Galli,
  • Daniele Giovanni Ghiglioni,
  • Luciana Indinnimeo,
  • Ahmad Kantar,
  • Adima Lamborghini,
  • Amelia Licari,
  • Riccardo Lubrano,
  • Stefano Luciani,
  • Francesco Macrì,
  • Gianluigi Marseglia,
  • Alberto Giuseppe Martelli,
  • Luigi Masini,
  • Fabio Midulla,
  • Domenico Minasi,
  • Vito Leonardo Miniello,
  • Michele Miraglia del Giudice,
  • Sergio Renzo Morandini,
  • Germana Nardini,
  • Agostino Nocerino,
  • Elio Novembre,
  • Giovanni Battista Pajno,
  • Francesco Paravati,
  • Giorgio Piacentini,
  • Cristina Piersantelli,
  • Gabriella Pozzobon,
  • Giampaolo Ricci,
  • Valter Spanevello,
  • Renato Turra,
  • Stefania Zanconato,
  • Melissa Borrelli,
  • Alberto Villani,
  • Giovanni Corsello,
  • Giuseppe Di Mauro,
  • Diego Peroni

DOI
https://doi.org/10.1186/s13052-021-01013-8
Journal volume & issue
Vol. 47, no. 1
pp. 1 – 24

Abstract

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Abstract Background In 2019, a multidisciplinary panel of experts from eight Italian scientific paediatric societies developed a consensus document for the use of inhaled corticosteroids in the management and prevention of the most common paediatric airways disorders. The aim is to provide healthcare providers with a multidisciplinary document including indications useful in the clinical practice. The consensus document was intended to be addressed to paediatricians who work in the Paediatric Divisions, the Primary Care Services and the Emergency Departments, as well as to Residents or PhD students, paediatric nurses and specialists or consultants in paediatric pulmonology, allergy, infectious diseases, and ear, nose, and throat medicine. Methods Clinical questions identifying Population, Intervention(s), Comparison and Outcome(s) were addressed by methodologists and a general agreement on the topics and the strength of the recommendations (according to the GRADE system) was obtained following the Delphi method. The literature selection included secondary sources such as evidence-based guidelines and systematic reviews and was integrated with primary studies subsequently published. Results The expert panel provided a number of recommendations on the use of inhaled corticosteroids in preschool wheezing, bronchial asthma, allergic and non-allergic rhinitis, acute and chronic rhinosinusitis, adenoid hypertrophy, laryngitis and laryngospasm. Conclusions We provided a multidisciplinary update on the current recommendations for the management and prevention of the most common paediatric airways disorders requiring inhaled corticosteroids, in order to share useful indications, identify gaps in knowledge and drive future research.

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