Frontiers in Microbiology (Mar 2021)

Outer Membrane Vesicles of Gram-Negative Bacteria: An Outlook on Biogenesis

  • Eric Daniel Avila-Calderón,
  • Eric Daniel Avila-Calderón,
  • María del Socorro Ruiz-Palma,
  • María del Socorro Ruiz-Palma,
  • Ma. Guadalupe Aguilera-Arreola,
  • Norma Velázquez-Guadarrama,
  • Enrico A. Ruiz,
  • Zulema Gomez-Lunar,
  • Sharon Witonsky,
  • Sharon Witonsky,
  • Araceli Contreras-Rodríguez

DOI
https://doi.org/10.3389/fmicb.2021.557902
Journal volume & issue
Vol. 12

Abstract

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Outer membrane vesicles (OMVs) from Gram-negative bacteria were first described more than 50 years ago. However, the molecular mechanisms involved in biogenesis began to be studied only in the last few decades. Presently, the biogenesis and molecular mechanisms for their release are not completely known. This review covers the most recent information on cellular components involved in OMV biogenesis, such as lipoproteins and outer membrane proteins, lipopolysaccharide, phospholipids, quorum-sensing molecules, and flagella.

Keywords