Journal of Cytology (Jan 2011)

Extranodal manifestation of Rosai-Dorfman disease with bilateral ocular involvement

  • Chayanika Kala,
  • Asha Agarwal,
  • Sanjay Kala

DOI
https://doi.org/10.4103/0970-9371.83473
Journal volume & issue
Vol. 28, no. 3
pp. 131 – 133

Abstract

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Rosai-Dorfman disease, that is, sinus histiocytosis with massive lymphadenopathy is a benign systemic proliferative disorder of histiocytes. The typical clinical presentation of the disease includes bilateral painless massive lymphadenopathy, fever and polyclonal hypergammaglobulinemia. Extranodal involvement is present in only a few cases and skin lesions are the most common form of extranodal disease. However, purely cutaneous Rosai-Dorfman disease is uncommon. In this study, we describe a 10-year-old child presenting with bilateral ocular involvement.

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