An exploration of the effects of Commiphora glileadenis on a Streptococcus mutans biofilm

Abstract

Streptococcus mutans (S. mutans) is an important bacterium involved in the first steps of dental biofilm formation with subsequent initiation of several oral diseases. Aim: To evaluate the influence of Myrrh plant extract on S. mutans and its biofilm formation. Material and Methods: The antibacterial activity of the Myrrh prepared plant extract was tested against S. mutans using disc diffusion method. The ability of the Myrrh plant extract to inhibit biofilm formation of S. mutans was also determined. Results: showed the ability of the tested Myrrh oil plant extract to cease the bacterial growth. The recorded clear zone is 11 mm with extract concentration 42.5%. Myrrh extract was able to inhibit the S. mutans biofilm formation in 78.5% inhibition percentage on fibroblast cellular viability. Conclusion: Myrrh plant extract has promising antibacterial effect as well as on biofilm inhibition of S. mutans. The significant antimicrobial effect of the Myrrh plant extract indicates about its promise in controlling S. mutans biofilm, which has suspected role in the etiology of dental caries and periodontal diseases.

Keywords

• Dental biofilm
• myrrh extract
• Streptococcus mutans
• Southwestern Saudi Arabia