Nature Communications (Nov 2022)
Spatially resolved gene regulatory and disease-related vulnerability map of the adult Macaque cortex
- Ying Lei,
- Mengnan Cheng,
- Zihao Li,
- Zhenkun Zhuang,
- Liang Wu,
- Yunong sun,
- Lei Han,
- Zhihao Huang,
- Yuzhou Wang,
- Zifei Wang,
- Liqin Xu,
- Yue Yuan,
- Shang Liu,
- Taotao Pan,
- Jiarui Xie,
- Chuanyu Liu,
- Giacomo Volpe,
- Carl Ward,
- Yiwei Lai,
- Jiangshan Xu,
- Mingyue Wang,
- Hao Yu,
- Haixi Sun,
- Qichao Yu,
- Liang Wu,
- Chunqing Wang,
- Chi Wai Wong,
- Wei Liu,
- Liangzhi Xu,
- Jingkuan Wei,
- Dandan Chen,
- Zhouchun Shang,
- Guibo Li,
- Kun Ma,
- Le Cheng,
- Fei Ling,
- Tao Tan,
- Kai Chen,
- Bosiljka Tasic,
- Michael Dean,
- Weizhi Ji,
- Huanming Yang,
- Ying Gu,
- Miguel A. Esteban,
- Yuxiang Li,
- Ao Chen,
- Yuyu Niu,
- Hongkui Zeng,
- Yong Hou,
- Longqi Liu,
- Shiping Liu,
- Xun Xu
Affiliations
- Ying Lei
- BGI-Hangzhou
- Mengnan Cheng
- BGI-Hangzhou
- Zihao Li
- BGI-Hangzhou
- Zhenkun Zhuang
- BGI-Hangzhou
- Liang Wu
- BGI-Shenzhen
- Yunong sun
- BGI-Hangzhou
- Lei Han
- BGI-Hangzhou
- Zhihao Huang
- BGI-Shenzhen
- Yuzhou Wang
- BGI-Shenzhen
- Zifei Wang
- BGI-Shenzhen
- Liqin Xu
- BGI-Shenzhen
- Yue Yuan
- BGI-Hangzhou
- Shang Liu
- BGI-Shenzhen
- Taotao Pan
- BGI-Shenzhen
- Jiarui Xie
- BGI-Shenzhen
- Chuanyu Liu
- BGI-Hangzhou
- Giacomo Volpe
- Hematology and Cell Therapy Unit, IRCCS-Istituto Tumori “Giovanni Paolo II”. Viale O Flacco 65
- Carl Ward
- Laboratory of Integrative biology, Guangzhou Institutes of Biomedicine and Health, CAS
- Yiwei Lai
- BGI-Hangzhou
- Jiangshan Xu
- BGI-Hangzhou
- Mingyue Wang
- BGI-Hangzhou
- Hao Yu
- BGI-Shenzhen
- Haixi Sun
- BGI-Shenzhen
- Qichao Yu
- BGI-Shenzhen
- Liang Wu
- BGI-Shenzhen
- Chunqing Wang
- BGI-Shenzhen
- Chi Wai Wong
- Huazhen Biosciences
- Wei Liu
- Huazhen Biosciences
- Liangzhi Xu
- Huazhen Biosciences
- Jingkuan Wei
- Yunnan Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology
- Dandan Chen
- BGI-GenoImmune, BGI-Shenzhen
- Zhouchun Shang
- BGI-Shenzhen
- Guibo Li
- BGI-Shenzhen
- Kun Ma
- BGI-Shenzhen
- Le Cheng
- BGI-Yunnan, BGI-Shenzhen
- Fei Ling
- School of Biology and Biological Engineering, South China University of Technology
- Tao Tan
- Yunnan Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology
- Kai Chen
- Yunnan Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology
- Bosiljka Tasic
- Allen Institute for Brain Science
- Michael Dean
- Cancer and Inflammation Program, National Cancer Institute at Frederick, Building 560
- Weizhi Ji
- Yunnan Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology
- Huanming Yang
- BGI-Shenzhen
- Ying Gu
- BGI-Hangzhou
- Miguel A. Esteban
- BGI-Hangzhou
- Yuxiang Li
- BGI-Shenzhen
- Ao Chen
- BGI-Shenzhen
- Yuyu Niu
- Yunnan Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology
- Hongkui Zeng
- Allen Institute for Brain Science
- Yong Hou
- BGI-Shenzhen
- Longqi Liu
- BGI-Hangzhou
- Shiping Liu
- BGI-Hangzhou
- Xun Xu
- BGI-Hangzhou
- DOI
- https://doi.org/10.1038/s41467-022-34413-3
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 20
Abstract
Cell type epigenetic and topographic information of primate brain is lacking. Here, authors identified transcriptional regulatory network, gradient expression pattern and disease vulnerability at cell type level in PFC, M1 and V1 of monkey brain by snRNAseq, snATAC-seq and Stereo-seq.
