Three mechanisms control E-cadherin localization to the zonula adherens

Innokenty Woichansky; Carlo Antonio Beretta; Nicola Berns; Veit Riechmann

doi:10.1038/ncomms10834

Nature Communications (Mar 2016)

Three mechanisms control E-cadherin localization to the zonula adherens

Innokenty Woichansky,
Carlo Antonio Beretta,
Nicola Berns,
Veit Riechmann

Affiliations

Innokenty Woichansky: Department of Cell and Molecular Biology and Division of Signaling and Functional Genomics at the German Cancer Research Center (DKFZ), Medical Faculty Mannheim, Heidelberg University
Carlo Antonio Beretta: Heidelberg University, COS and Nikon Imaging Center at the University of Heidelberg
Nicola Berns: Department of Cell and Molecular Biology and Division of Signaling and Functional Genomics at the German Cancer Research Center (DKFZ), Medical Faculty Mannheim, Heidelberg University
Veit Riechmann: Department of Cell and Molecular Biology and Division of Signaling and Functional Genomics at the German Cancer Research Center (DKFZ), Medical Faculty Mannheim, Heidelberg University

DOI: https://doi.org/10.1038/ncomms10834
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 11

Abstract

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E-cadherin is an adhesion molecule mediating cell-cell adhesion; correct localization is important but how localization is controlled is not clear. Here the authors use Drosophilaas a model system to distinguish three distinct trafficking pathways that direct E-cadherin to the zonula adherens.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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