Adrenocortical carcinoma with extension to the inferior vena cava and right atrium: 20-month-old girl with TP53 mutation

Terry L. Levin, MD; Walter E. Berdon, MD; Daniel Weiser, MD; Raul C. Ribeiro, MD

doi:10.2484/rcr.v10i2.1084

Radiology Case Reports (Jan 2015)

Adrenocortical carcinoma with extension to the inferior vena cava and right atrium: 20-month-old girl with TP53 mutation

Terry L. Levin, MD,
Walter E. Berdon, MD,
Daniel Weiser, MD,
Raul C. Ribeiro, MD

Affiliations

Terry L. Levin, MD: Department of Radiology, Division of Pediatric Radiology, Children's Hospital at Montefiore Medical Center, Bronx, NY
Walter E. Berdon, MD: Department of Radiology, Division of Pediatric Radiology, Columbia Presbyterian Medical Center, New York, NY
Daniel Weiser, MD: Department of Pediatrics, Division of Pediatric Hematology and Oncology, Children's Hospital at Montefiore Medical Center, Bronx, NY
Raul C. Ribeiro, MD: Department of Oncology, Leukemia and Lymphoma Division, St. Jude's Children's Research Hospital, Memphis TN

DOI: https://doi.org/10.2484/rcr.v10i2.1084
Journal volume & issue: Vol. 10, no. 2

Abstract

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A 20-month-old female presented with respiratory distress and a right adrenal mass extending into the inferior vena cava and right atrium. The mass was initially thought to be neuroblastoma. Pathology later revealed adrenocortical carcinoma. Inferior vena cava extension is far more common in adrenocortical carcinoma than neuroblastoma, and its presence should prompt clinical and laboratory evaluation for an adrenocortical tumor. The genetic findings in TP53 associated with this disease are discussed.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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