Yeast cell wall mannan structural features, biological activities, and production strategies
Kwang-Rim Baek,
Sudha Rani Ramakrishnan,
Soo-Jung Kim,
Seung-Oh Seo
Affiliations
Kwang-Rim Baek
Department of Food Science and Biotechnology, Seoul National University of Science and Technology, Seoul, 01811, Republic of Korea
Sudha Rani Ramakrishnan
Department of Integrative Food, Bioscience, and Biotechnology, and Research Center for Biological Cybernetics, Chonnam National University, Gwangju, 61186, Republic of Korea; Department of Biotechnology, Anna University, Chennai, 600025, India
Soo-Jung Kim
Department of Integrative Food, Bioscience, and Biotechnology, and Research Center for Biological Cybernetics, Chonnam National University, Gwangju, 61186, Republic of Korea; Corresponding author. Department of Integrative Food, Bioscience, and Biotechnology, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju, 61186, Republic of Korea.
Seung-Oh Seo
Department of Food Science and Biotechnology, Seoul National University of Science and Technology, Seoul, 01811, Republic of Korea; Research Institute of Food and Biotechnology, Seoul, 01811, Republic of Korea; Corresponding author. Department of Food Science and Biotechnology, Seoul National University of Science and Technology, 232 Gongneung-ro, Nowon-gu, Seoul, 01811, Republic of Korea.
Mannan and outer structural yeast cell wall polysaccharides have recently garnered attention for their health defense and cosmetic applications. In addition, many studies have confirmed that yeast cell wall mannans exhibit various biological activities, such as antioxidant, immune regulation, reducing hyperlipidemia, and gut health promotion. This paper elucidates yeast cell wall mannan structural features, biological activities, underlying molecular mechanisms, and biosynthesis. Moreover, mannan-overproducing strategies through yeast strain engineering are emphasized and discussed. This review will provide a scientific basis for yeast cell wall mannan research and industrial applications.
