Alzheimer’s & Dementia: Translational Research & Clinical Interventions (Jan 2021)
The Worldwide Alzheimer's Disease Neuroimaging Initiative: ADNI‐3 updates and global perspectives
- Christopher J. Weber,
- Maria C. Carrillo,
- William Jagust,
- Clifford R. Jack Jr,
- Leslie M. Shaw,
- John Q. Trojanowski,
- Andrew J. Saykin,
- Laurel A. Beckett,
- Cyrille Sur,
- Naren P. Rao,
- Patricio Chrem Mendez,
- Sandra E. Black,
- Kuncheng Li,
- Takeshi Iwatsubo,
- Chiung‐Chih Chang,
- Ana Luisa Sosa,
- Christopher C. Rowe,
- Richard J. Perrin,
- John C. Morris,
- Amanda M.B. Healan,
- Stephen E. Hall,
- Michael W. Weiner
Affiliations
- Christopher J. Weber
- Alzheimer's Association Chicago Illinois USA
- Maria C. Carrillo
- Alzheimer's Association Chicago Illinois USA
- William Jagust
- School of Public Health and Helen Wills Neuroscience Institute University of California Berkeley Berkeley California USA
- Clifford R. Jack Jr
- Department of Radiology Mayo Clinic Rochester Minnesota USA
- Leslie M. Shaw
- Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA
- John Q. Trojanowski
- Department of Pathology and Laboratory Medicine Perelman School of Medicine Institute on Aging Perelman School of Medicine Alzheimer's Disease Core Center, Perelman School of Medicine Udall Parkinson's Research Center Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA
- Andrew J. Saykin
- Department of Radiology and Imaging Sciences and the Indiana Alzheimer's Disease Research Center Department of Medical and Molecular Genetics Indiana University School of Medicine Indianapolis Indiana USA
- Laurel A. Beckett
- Division of Biostatistics Department of Public Health Sciences University of California Davis California USA
- Cyrille Sur
- Merck Research Laboratories Merck Kenilworth New Jersey USA
- Naren P. Rao
- Department of Psychiatry National Institute of Mental Health and Neurosciences Bengaluru Karnataka India
- Patricio Chrem Mendez
- Centro de Memoria FLENI Montañeses, 2325 (C1428AQK), Bs As Buenos Aires Argentina
- Sandra E. Black
- Department of Medicine (Neurology) Hurvitz Brain Sciences Program Canadian Partnership for Stroke Recovery, and LC Campbell Cognitive Neurology Research Unit Hurvitz Brain Sciences Research Program Sunnybrook Research Institute Sunnybrook Health Sciences Centre University of Toronto Toronto Canada
- Kuncheng Li
- Department of Radiology Xuanwu Hospital of Capital Medical University Beijing China
- Takeshi Iwatsubo
- Department of Neuropathology Graduate School of Medicine The University of Tokyo Tokyo Japan
- Chiung‐Chih Chang
- Department of General Neurology and Institute for Translational Research in Biomedicine Kaohsiung Chang Gung Memorial Hospital Chang Gung University College of Medicine Kaohsiung Taiwan
- Ana Luisa Sosa
- National Institute of Neurology and Neurosurgery of Mexico Mexico City Mexico
- Christopher C. Rowe
- Department of Molecular Imaging and Therapy Austin Health and Florey Department of Neuroscience and Mental Health University of Melbourne Melbourne Victoria Australia
- Richard J. Perrin
- Charles F. and Joanne Knight Alzheimer Disease Research Center Department of Pathology and Immunology Department of Neurology Washington University School of Medicine Saint Louis Missouri USA
- John C. Morris
- Charles F. and Joanne Knight Alzheimer Disease Research Center Department of Neurology Washington University School of Medicine Saint Louis Missouri USA
- Amanda M.B. Healan
- Independent Science Writer and Editor Nashville Tennessee USA
- Stephen E. Hall
- Alzheimer's Association Chicago Illinois USA
- Michael W. Weiner
- Department of Veterans Affairs Medical Center Center for Imaging of Neurodegenerative Diseases Department of Radiology Department of Medicine Department of Psychiatry Department of Neurology University of California San Francisco California USA
- DOI
- https://doi.org/10.1002/trc2.12226
- Journal volume & issue
-
Vol. 7,
no. 1
pp. n/a – n/a
Abstract
Abstract The Worldwide Alzheimer's Disease Neuroimaging Initiative (WW‐ADNI) is a collaborative effort to investigate imaging and biofluid markers that can inform Alzheimer's disease treatment trials. It is a public‐private partnership that spans North America, Argentina, Australia, Canada, China, Japan, Korea, Mexico, and Taiwan. In 2004, ADNI researchers began a naturalistic, longitudinal study that continues today around the globe. Through several successive phases (ADNI‐1, ADNI‐GO, ADNI‐2, and ADNI‐3), the study has fueled amyloid and tau phenotyping and refined neuroimaging methodologies. WW‐ADNI researchers have successfully standardized analyses and openly share data without embargo, providing a rich data set for other investigators. On August 26, 2020, the Alzheimer's Association convened WW‐ADNI researchers who shared updates from ADNI‐3 and their vision for ADNI‐4.
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