PLoS ONE (Jan 2014)

Feasibility and safety of fiber optic micro-imaging in canine peripheral airways.

  • Yijun Liu,
  • Bingbing Yan,
  • Ziyang Huang,
  • Rui Guo,
  • Jingxing Wu,
  • Xun Liu,
  • Kaiqing Yao,
  • Fajin Lv,
  • Huisheng Deng

DOI
https://doi.org/10.1371/journal.pone.0084829
Journal volume & issue
Vol. 9, no. 1
p. e84829

Abstract

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PURPOSE: To assess the feasibility and safety of imaging canine peripheral airways (0.05). Comparing pre-manipulation and post-manipulation values, SpO2 (F = 13.06, P<0.05) and PaO2 (F = 3.01, P = 0.01) were decreased, whereas RR (F = 3.85, P<0.05) was elevated during the manipulation. (3) Self-limited bleeding was observed in one dog; severe bleeding or other complications did not occur. CONCLUSION: Although the new apparatus had little effect on SpO2, PaO2 and RR, it can probe into small peripheral airways (<1 mm), which may provide a new platform for the early diagnosis of bronchiolar diseases.