Avoidance Of Mechanisms Of Innate Immune Response By Neisseria Gonorrhoeae

Abstract

Neisseria gonorrhoeae (gonococcus) is a Gram-negative bacteria and an etiological agent of the sexually transmitted disease – gonorrhea. N. gonorrhoeae possesses many mechanism to evade the innate immune response of the human host. Most are related to serum resistance and avoidance of complement killing. However the clinical symptoms of gonorrhea are correlated with a significant presence of neutrophils, whose response is also insufficient and modulated by gonococci.

Keywords

• bacterial pathogenesis
• inflammation
• innate immune response
• bakteryjna patogeneza
• stan zapalny
• wrodzona odpowiedź immunologiczna