Mo@ZIF-8 nanozyme preparation and its antibacterial property evaluation

Zheng Lian; Zheng Lian; Chunqing Lu; Jiangqi Zhu; Jiangqi Zhu; Xining Zhang; Ting Wu; Youlin Xiong; Zhiyi Sun; Rong Yang

doi:10.3389/fchem.2022.1093073

Frontiers in Chemistry (Nov 2022)

Mo@ZIF-8 nanozyme preparation and its antibacterial property evaluation

Zheng Lian,
Zheng Lian,
Chunqing Lu,
Jiangqi Zhu,
Jiangqi Zhu,
Xining Zhang,
Ting Wu,
Youlin Xiong,
Zhiyi Sun,
Rong Yang

Affiliations

Zheng Lian: School of Criminal Investigation, People’s Public Security University of China, Beijing, China
Zheng Lian: CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Center of Materials Science and Optoelectronics Engineering, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing, China
Chunqing Lu: School of Criminal Investigation, People’s Public Security University of China, Beijing, China
Jiangqi Zhu: School of Criminal Investigation, People’s Public Security University of China, Beijing, China
Jiangqi Zhu: Institute of Evidence Law and Forensic Science, China University of Politic Science and Law, Beijing, China
Xining Zhang: CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Center of Materials Science and Optoelectronics Engineering, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing, China
Ting Wu: CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Center of Materials Science and Optoelectronics Engineering, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing, China
Youlin Xiong: CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Center of Materials Science and Optoelectronics Engineering, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing, China
Zhiyi Sun: School of Criminal Investigation, People’s Public Security University of China, Beijing, China
Rong Yang: CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Center of Materials Science and Optoelectronics Engineering, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing, China

DOI: https://doi.org/10.3389/fchem.2022.1093073
Journal volume & issue: Vol. 10

Abstract

Read online

Types of nanozymes can produce free radicals and/or reactive oxygen species (ROS) to serve as broad spectrum antibacterial materials. Developing nanozyme-based antibacterial materials with good biocompatibility exhibits promising application prospects. In this study, we doped Mo to ZIF-8 (both components have good biocompatibility) to prepare a new nanozyme, Mo@ZIF-8, which can produce hydroxyl radicals (•OH) triggered by a low dosage of hydrogen peroxide (H2O2), exhibiting effective antibacterial capability against both Gram-negative bacteria (Escherichia coli) and Gram-positive bacteria (Staphylococcus aureus). This work provides a reference for the design of antibacterial nanozymes with good biocompatibility.

Published in Frontiers in Chemistry

ISSN: 2296-2646 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Science: Chemistry
Website: http://journal.frontiersin.org/journal/chemistry

About the journal

Abstract

Keywords