Journal of Medical Case Reports (Nov 2021)

Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report

  • Huiping Li,
  • Fang Yuan,
  • Yaming Du,
  • Tao Pan,
  • Wanxin Wen,
  • Shaoxue Li,
  • Lixin Wang,
  • Aili Lu

DOI
https://doi.org/10.1186/s13256-021-03139-z
Journal volume & issue
Vol. 15, no. 1
pp. 1 – 5

Abstract

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Abstract Background Progressive supranuclear palsy is a neurodegenerative condition that worsens over time. Given the lack of targeted treatments, patients with severe progressive supranuclear palsy have very low life expectancy. Case presentation We present a case of a 61-year-old Chinese man with severe progressive supranuclear palsy and treated with umbilical cord blood stem cells transplantation. After the umbilical cord blood stem cells therapy, his neurologic symptoms stopped deteriorating, his muscle rigidity was mildly improved, and he remains alive for more than 8 years. Conclusions Umbilical cord blood stem cells transplantation may be an alternative therapy for patients with severe progressive supranuclear palsy.

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