Acta Biomedica Scientifica (Feb 2016)

Features of reaction of coagulation hemostasis in children with pneumonia

  • N. A. Dorokhov,
  • E. V. Skudarnov,
  • D. A. Antropov

DOI
https://doi.org/10.12737/21478
Journal volume & issue
Vol. 1, no. 1
pp. 12 – 15

Abstract

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The article presents data from a study of 161 child with pneumonia. Two groups of patients with uncomplicated pneumonia and pneumonia with pleural pulmonary complication were formed. The study of coagulation hemostasis was realized in the studied groups. It was found that in children with uncomplicated pneumonia levels of SFMC and D-dimer were significantly higher than in normal conditions that indicates activation of coagulation hemostasis. When complicated by pneumonia hemostasis matches the current intravascular coagulation: thrombocytosis, increased levels of fibrinogen, hypo-or hypercoagulation on aPTT, changing TV thrombinemia (SFMC is 5 times higher than normal), and increased level of D-dimer, inhibition of fibrinolysis, which indicates more pronounced activation of coagulation in children with pneumonia.

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