Safety and Efficacy of Eucaloric Very Low-Carb Diet (EVLCD) in Type 1 Diabetes: A One-Year Real-Life Retrospective Experience

Andrea Kleiner; Barbara Cum; Livia Pisciotta; Ivan Raffaele Cincione; Ludovica Cogorno; Amalia Prigione; Antonio Tramacere; Andrea Vignati; Luca Carmisciano; Samir Giuseppe Sukkar

doi:10.3390/nu14153208

Nutrients (Aug 2022)

Safety and Efficacy of Eucaloric Very Low-Carb Diet (EVLCD) in Type 1 Diabetes: A One-Year Real-Life Retrospective Experience

Andrea Kleiner,
Barbara Cum,
Livia Pisciotta,
Ivan Raffaele Cincione,
Ludovica Cogorno,
Amalia Prigione,
Antonio Tramacere,
Andrea Vignati,
Luca Carmisciano,
Samir Giuseppe Sukkar

Affiliations

Andrea Kleiner: Salus AlpeAdria Diabetes Center, 33100 Udine, Italy
Barbara Cum: Salus AlpeAdria Diabetes Center, 33100 Udine, Italy
Livia Pisciotta: Dietetics and Clinical Nutrition Unit, IRCCS Policlinic Hospital San Martino, 16132 Genoa, Italy
Ivan Raffaele Cincione: Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy
Ludovica Cogorno: Dietetics and Clinical Nutrition Unit, IRCCS Policlinic Hospital San Martino, 16132 Genoa, Italy
Amalia Prigione: Department of Internal Medicine, University of Genoa, 16132 Genoa, Italy
Antonio Tramacere: Department of Internal Medicine, University of Genoa, 16132 Genoa, Italy
Andrea Vignati: Department of Internal Medicine, University of Genoa, 16132 Genoa, Italy
Luca Carmisciano: Department of Health Sciences (DISSAL), Section of Biostatistics, University of Genoa, Via Pastore, 16132 Genoa, Italy
Samir Giuseppe Sukkar: Dietetics and Clinical Nutrition Unit, IRCCS Policlinic Hospital San Martino, 16132 Genoa, Italy

DOI: https://doi.org/10.3390/nu14153208
Journal volume & issue: Vol. 14, no. 15
p. 3208

Abstract

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A eucaloric very low carbohydrate diet (EVLCD) is a diet with a daily caloric intake equal to the total daily energy expenditure (TDEE) with a carbohydrate content of p p p < 0.01) in the units of daily insulin (from 36.7± 14.9 IU to 28.9 ±9.1 IU) A reduction from 54% to 24% in clinical level 2 hypoglycemia episodes was reported. No cases of severe hypoglycemia or ketoacidosis were observed. The results of the study support that EVLCD in DM 1 seems safe and effective when adopted under tight medical supervision.

Published in Nutrients

ISSN: 2072-6643 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Technology: Home economics: Nutrition. Foods and food supply
Website: https://www.mdpi.com/journal/nutrients

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