Nature Communications (Jul 2020)

A universal and independent synthetic DNA ladder for the quantitative measurement of genomic features

  • Andre L. M. Reis,
  • Ira W. Deveson,
  • Ted Wong,
  • Bindu Swapna Madala,
  • Chris Barker,
  • James Blackburn,
  • Esteban Marcellin,
  • Tim R. Mercer

DOI
https://doi.org/10.1038/s41467-020-17445-5
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 11

Abstract

Read online

Standard units of measurement are required for a quantitative description of the genome. Here, the authors present a universal synthetic DNA ladder that can measure genetic abundance in next-generation sequencing libraries.