Disease Models & Mechanisms (Oct 2022)
Integrated multi-omics analysis of Huntington disease identifies pathways that modulate protein aggregation
- Sai S. Pradhan,
- Sai M. Thota,
- Saiswaroop Rajaratnam,
- Sai K. S. Bhagavatham,
- Sujith K. Pulukool,
- Sriram Rathnakumar,
- Kanikaram S. Phalguna,
- Rajesh B. Dandamudi,
- Ashish Pargaonkar,
- Prasanth Joseph,
- E. V. Joshy,
- Venketesh Sivaramakrishnan
Affiliations
- Sai S. Pradhan
- Disease Biology Lab, Department of Biosciences, Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, Anantapur, Andhra Pradesh, India 515134
- Sai M. Thota
- Disease Biology Lab, Department of Biosciences, Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, Anantapur, Andhra Pradesh, India 515134
- Saiswaroop Rajaratnam
- Disease Biology Lab, Department of Biosciences, Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, Anantapur, Andhra Pradesh, India 515134
- Sai K. S. Bhagavatham
- Disease Biology Lab, Department of Biosciences, Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, Anantapur, Andhra Pradesh, India 515134
- Sujith K. Pulukool
- Disease Biology Lab, Department of Biosciences, Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, Anantapur, Andhra Pradesh, India 515134
- Sriram Rathnakumar
- Disease Biology Lab, Department of Biosciences, Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, Anantapur, Andhra Pradesh, India 515134
- Kanikaram S. Phalguna
- Disease Biology Lab, Department of Biosciences, Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, Anantapur, Andhra Pradesh, India 515134
- Rajesh B. Dandamudi
- Department of Chemistry, Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, Anantapur, Andhra Pradesh 515 134, India
- Ashish Pargaonkar
- Application Division, Agilent Technologies Ltd., Bengaluru 560048, India
- Prasanth Joseph
- Application Division, Agilent Technologies Ltd., Bengaluru 560048, India
- E. V. Joshy
- Department of Neurology, Sri Sathya Sai Institute of Higher Medical Sciences, Whitefield, Bengaluru, Karnataka 560066, India
- Venketesh Sivaramakrishnan
- Disease Biology Lab, Department of Biosciences, Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, Anantapur, Andhra Pradesh, India 515134
- DOI
- https://doi.org/10.1242/dmm.049492
- Journal volume & issue
-
Vol. 15,
no. 10
Abstract
No abstracts available.Keywords
- huntington disease
- metabolomics
- multi-omics analysis
- neurodegenerative disease
- protein aggregation
- hd yeast model
