Effect of 12 Weeks Walking on Inflammatory Factors in Postmenopausal Women with Breast Cancer

Abstract

Introduction: The aim of this study was to investigate the effect of 12 weeks walking on inflammatory factorsin postmenopausal women with breast cancer. Methods: nineteen postmenopausal women with breast cancerwith range age of 50 to 65 years (55.05±2.7) who received surgery, chemotherapy and radiation-therapy withcurrent hormone therapy by letrozol were randomly divided into two groups; (Control:8, experimental:11).Subjects in the experimental group were performed 12 weeks exercise training program which consisted of 25to 45 minutes of walking with intensity of %45 -%65 of THR, three times a week. The control group did notparticipate in exercise training. In pre and post tests, CRP, IL-6, TNF-α, anthropometric variables (bodyweight, BMI, WHR), body fat percentage and Vo2peak were measured in both groups. Data were analyzedthrough analysis of covariance (ANCOVA) and t test (P0.05). After 12 weeks, body weight was decreased in the experimental groupand was increased in control group; BMI was decreased in the experimental group and was increased in controlgroup. Also, VO2peak was increased in the experimental group and was decreased in control group. Conclusion:It can be concluded that 12 weeks walking there have no effect on inflammatory factors in postmenopausalwomen with breast cancer, but may improve VO2peak, body weight and BMI.

Keywords

• breast cancer
• inflammatory factors
• walking