Relation Between Systemic Immune-Inflammation Index and Post PCI Bleeding Risk in STEMI Patients

Abstract

Objectives: To investigate the relationship between the systemic immune-inflammation index (SII) and bleeding complications in ST-elevated myocardial infarction (STEMI) after percutaneous coronary intervention (pPCI). Materials and Methods: This retrospective study included 1778 patients who presented with STEMI and underwent pPCI. Patients were divided into two groups: those who developed bleeding and those who did not. The SII values and CRUSADE bleeding score were calculated. Results: In the group with bleeding complications, the ages were 62 (50-73), and 69.6% were male. Multivariate analysis identified age 1.031(1.015-1.048) - p<0.001, basal creatinine 1.789 (1.366-2.342) - p<0.001, SII 1.163 (1.028-1.315)- p=0.013 as significant predictors of bleeding complications. Conclusion: The easily calculated SII may help predict bleeding complications in STEMI patients undergoing pPCI.

Keywords

• st elevation myocardial infarction
• bleeding
• systemic immune-inflammation index