PROSPECTS FOR THE USE OF CONTRACEPTIVE VAGINAL PATCH ZB-06

Abstract

With the high frequency of unplanned pregnancies in many countries, there is an urgent need for more affordable and effective contraceptives. In recent years, scientists around the world have been actively developing new methods of barrier contraception. This method is very simple and convenient due to the fact that it has no systemic effect, side effects are minimized, and a woman can use it when she needs it. In order to fill the gap in this niche, scientists have developed the ZB-06 vaginal contraceptive film containing the HC4-N human contraceptive antibody (HPA). Purpose. Study literature sources on the use of contraceptive vaginal film ZB-06. Materials and methods. Materials from PubMed and PubMedCentral resources of the US National Library of Medicine, Google Scholar, Elsevier Clinical Key and Elsevier Science Direct were used to analyze the literature. For the analysis of scientific literature, a qualitative method based on content analysis was used, namely, the definition of units of analysis - headings, annotations and keywords of articles; calculation of the frequency and percentage distribution of analysis units by analysis categories using the Excel program; interpretation and generalization of analysis results. Results. This review presents summarized research results that demonstrate that the ZB-06 contraceptive film has a number of advantages and disadvantages. This method of contraception provides effective levels of mucosal antisperm antibodies for at least 3 hours after use. Conclusion. Contraceptive vaginal film ZB-06 is an innovative, non-hormonal, topically applied vaginal film (containing HC4-N PPA), which in phase 1 of the study showed a high level of effectiveness and met the safety requirements for contraceptives.

Keywords

• contraception
• contraceptive antibody
• postcoital test
• motile sperm