Essential hypertensive controlled and normotensive patients. If there are differences?

Abstract

Ambulatory blood pressure monitoring (ABPM) is a modern method of blood pressure (BP) investigation recommended by international scientific associations for diagnostics of essential hypertension (EH). However, there are some methodological aspects which are not regulated. Particularly, ABPM parameters have not yet established for those patients in different age groups and pathologies. The aim of the study was to determine peculiarities of ABPM parameters in treated controlled hypertensive and normotensive patients. Materials and methods. 71 patients were included into the study and divided into two groups according to the level of 24-h systolic BP (SBP) and 24-h diastolic BP (DBP). There were 50 controlled patients with EH in the first group and 21 normotensive individuals without EH in the second group. Results. In EH patients and normotensive individuals we had statistician difference of such parameters, like the hypertension time index (TI) of day SBP parameters (20 (8–31) % vs. 8 (4–18) %; р=0.040); of the square index (SI) of hypertension (24 (11–41) mm2/h vs. 8 (2–23) mm2/h; р=0.021); of the square index normalized (SIN) of hypertension (1.4 (0.6–2.4) U vs. 0.4 (0.1–1.2) U; р=0.018,) and the morning surge of SBP (45±14 mm Hg vs. 37±14 mm Hg; р=0.028, respectively). There is no different in other ABPM parameters. Conclusion. The present data shows that treated controlled hypertensive patients and individuals without EH have statistician difference only in daily SBP of hypertensive indexes (TI, SI, SIN) and the morning surge of SBP. The other ABPM parameters, included new one, such as the arterial stiffness index, did not represent statistical difference between groups.

Keywords

• Essential Hypertension
• Blood Pressure
• Ambulatory Blood Pressure Monitoring
• Ambulatory Arterial Stiffness Index